The present technology provides a method of manufacturing a pneumatic tire. The method of manufacturing a pneumatic tire uses a laminated sheet having a predetermined length and an inner liner layer formed from the laminated sheet through a step of cure-molding the tire with end portions of the laminated sheet lap-spliced. In the method, when at least the sheet made of thermoplastic resin or a thermoplastic resin composition obtained by blending the thermoplastic resin and the elastomer is cut into the predetermined length, the cutting is performed by using an edge tool having a non-sharp edge under a temperature condition not lower than 60° C. and not higher than a melting point of the thermoplastic resin.