Intermediates and methods for the synthesis of halichondrin B analogs

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US09604993B2 Intermediates and methods for the synthesis of halichondrin B analogs 有权

Patent Title: Intermediates and methods for the synthesis of halichondrin B analogs
Application No.: US14624033

Application Date: 2015-02-17
Publication No.: US09604993B2

Publication Date: 2017-03-28
Inventor: Charles E. Chase , Atsushi Endo , Francis G. Fang , Jing Li
Applicant: Eisai R&D Management Co., Ltd.
Applicant Address: JP Tokyo
Assignee: Eisai R&D Management Co., Ltd.
Current Assignee: Eisai R&D Management Co., Ltd.
Current Assignee Address: JP Tokyo
Agency: Clark & Elbing LLP
Main IPC: C07D493/20
IPC: C07D493/20 ; A61K31/335 ; C07D307/28 ; C07D307/33 ; C07D493/08 ; C07D493/18

Abstract:

Methods of synthesizing intermediates useful for the synthesis of halichondrin B analogs are described.

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