A boost converter circuit receives an input power supply voltage and produces an output boosted supply voltage. The circuit includes a voltage regulator, boosting circuitry, and a timing controller. The voltage regulator provides a regulated voltage to the boosting circuitry, which controls switching a transistor to drive the output boosted supply voltage; and the timing controller controls switching the boost circuit from the start-up mode to the normal operation mode. In start-up mode, the regulated voltage is generated from the input power supply voltage. During normal operation mode, the regulated voltage is generated from the output boosted supply voltage. The circuitry performs a low-power start-up when the input power supply voltage is low, and maintains efficient low-power operation by driving the transistor to produce the output boosted supply voltage as the input power supply voltage decreases.