Fiber optic systems with an MR compatible mouse in an MR scanner room that connects to a fiber optic computer mouse interface that is attached to a fiber optic cable that connects to a USB port of a computer in the MR control room to allow the mouse in the MR scanner room to move a cursor on a monitor in communication with the computer in the control room of an MRI suite during an MRI guided surgical procedure. The fiber optic cable(s) can be routed though a conventional RF wall waveguide and avoids the need for additional holes in the penetration panel for connectors. The fiber optic systems can also include up converters and down converters for providing fiber optic video signals from cameras in the MR scanner room to display video signal on the monitor.