- 专利标题: Substituted indazole derivatives active as kinase inhibitors
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申请号: US14971372申请日: 2015-12-16
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公开(公告)号: US09616059B2公开(公告)日: 2017-04-11
- 发明人: Andrea Lombardi Borgia , Maria Menichincheri , Paolo Orsini , Achille Panzeri , Ettore Perrone , Ermes Vanotti , Marcella Nesi , Chiara Marchionni
- 申请人: NERVIANO MEDICAL SCIENCES S.R.L.
- 申请人地址: IT Nerviano (MI)
- 专利权人: NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人: NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人地址: IT Nerviano (MI)
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 优先权: EP07112881 20070720
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61K45/06 ; C07D405/12 ; C07D231/56 ; C07D401/12 ; C07D401/14 ; C07D403/14 ; C07D405/04 ; C07D405/14
摘要:
Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.
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