Invention Grant
- Patent Title: Compositions and methods for detecting and treating colorectal cancer
-
Application No.: US14605519Application Date: 2015-01-26
-
Publication No.: US09618513B2Publication Date: 2017-04-11
- Inventor: Weiping Zou , Ilona Kryczek
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, SC
- Main IPC: G01N33/574
- IPC: G01N33/574 ; C07K16/24 ; A61K31/7076 ; A61K45/06 ; C12N15/113 ; C12Q1/68 ; A61K31/7105 ; A61K31/713
Abstract:
The present invention relates to compositions and methods for the detecting, treating, and empirically investigating the interaction between a subject's immune system and cancer stem cells. In particular, the present invention provides compositions and methods for using IL-22 cytokine signaling and/or downstream targets of IL-22 cytokine signaling (e.g., STAT3, DOT1L, SUZ12, EED) in the diagnosis, treatment, and empirical investigation of cancers characterized with cancer stem cells activated through IL-22 cytokine signaling.
Public/Granted literature
- US20150212088A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING COLORECTAL CANCER Public/Granted day:2015-07-30
Information query
IPC分类:
