发明授权
- 专利标题： Immunogenic compositions for the prevention and treatment of meningococcal disease
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申请号： US13455326申请日： 2012-04-25
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公开(公告)号： US09623101B2公开(公告)日： 2017-04-18
- 发明人: Gary W. Zlotnick , Leah Diane Fletcher , John Erwin Farley , Liesel A. Bernfield , Robert J. Zagursky , Benjamin J. Metcalf
- 申请人： Gary W. Zlotnick , Leah Diane Fletcher , John Erwin Farley , Liesel A. Bernfield , Robert J. Zagursky , Benjamin J. Metcalf
- 申请人地址： US NY New York
- 专利权人： Wyeth Holdings LLC
- 当前专利权人： Wyeth Holdings LLC
- 当前专利权人地址： US NY New York
- 代理商 Anna C. Chau
- 主分类号： A61K39/095
- IPC分类号： A61K39/095 ; A61K47/48 ; C07K14/22 ; C07K16/12 ; G01N33/569 ; C12N9/28 ; C12N9/40 ; C12N9/38 ; A61K39/39 ; A61K39/00
摘要：
The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.