A V-bank filter assembly and a replaceable air filter are provided. In one embodiment, the V-bank filter assembly includes a top panel and bottom panel coupled in a spaced apart relation, each of the top and bottom panels having a first edge and a second edge, a plurality of panel end seal struts extending between the top and bottom panels, each panel end seal struts having a first mating sealing feature facing the first edge of the top and bottom panels, the first mating sealing feature configured to sealingly engage a replaceable filter panel, wherein the plurality of panel end seal struts are located adjacent the second edge, and a plurality of filter panel receiving tracks defined between the top and bottom panels configured to align filter panels disposed in the tracks with a respective first mating sealing feature.