- 专利标题: Msp nanopores and related methods
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申请号: US14318072申请日: 2014-06-27
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公开(公告)号: US09624275B2公开(公告)日: 2017-04-18
- 发明人: Jens H. Gundlach , Michael Niederweis , Thomas Z. Butler , Mikhail Pavlenok , Mark A. Troll , Suja Sukumaran
- 申请人: University of Washington , The UAB Research Foundation
- 申请人地址: US WA Seattle US AL Birmingham
- 专利权人: University of Washington,The UAB Research Foundation
- 当前专利权人: University of Washington,The UAB Research Foundation
- 当前专利权人地址: US WA Seattle US AL Birmingham
- 代理机构: Christensen O'Connor Johnson Kindness PLLC
- 主分类号: A61K39/04
- IPC分类号: A61K39/04 ; A61K39/02 ; C12Q1/70 ; C07K14/35 ; C12N13/00 ; G01N33/68 ; C12Q1/68 ; G01N27/447 ; G01N33/487
摘要:
Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
公开/授权文献
- US20140308662A1 MSP NANOPORES AND RELATED METHODS 公开/授权日:2014-10-16
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