发明授权
- 专利标题: Regioselectively substituted cellulose esters and efficient methods of preparing them
-
申请号: US14513855申请日: 2014-10-14
-
公开(公告)号: US09624311B2公开(公告)日: 2017-04-18
- 发明人: Kevin Edgar , Daiqiang Xu , Xueyan Zheng
- 申请人: Kevin Edgar , Daiqiang Xu , Xueyan Zheng
- 申请人地址: US VA Blacksburg
- 专利权人: VTIP Intellectual Properties, Inc.
- 当前专利权人: VTIP Intellectual Properties, Inc.
- 当前专利权人地址: US VA Blacksburg
- 代理机构: New River Valley IP Law, PC
- 代理商 Michele L. Mayberry
- 主分类号: C08B3/24
- IPC分类号: C08B3/24 ; C08B3/00 ; C08B3/06 ; C08J5/18 ; C08L1/10 ; C08B3/08 ; C08B3/16
摘要:
Embodiments of the invention provide regioselectively substituted carbohydrate and polysaccharide derivatives, such as cellulose esters, and methods for preparing them. Particular methods of the invention include deacylation of esters using tetrabutylammonium fluoride to obtain selective substitution at desired hydroxyl position(s) of the ester. Preferred is deacylation of an ester, which shows selectivity for removal of acyl groups from the ester of the secondary alcohols at C-2 and C-3, and which affords cellulose-6-O-esters with high regioselectivity by a simple one-step process employing no protective groups. Inventive regioselectively substituted cellulose esters can be prepared by such methods to obtain esters with the following anhydroglucose repeating units: wherein R1, R2, and R3 are each independently chosen from a hydrogen atom, and, whether substituted or unsubstituted, branched or unbranched, an alkanoyl group, an aroyl group, and a heteroaroyl group. In embodiments, the alkanoyl, aroyl and heteroaroyl groups can comprise from 1-20 carbon atoms.