An antenna switching method includes tuning respective signals provided to first and second antennas in a portable electronic device to at least one frequency band. The method may also include connecting the first antenna to an uplink signal path that is for transmissions through the first and second antennas, and performing impedance matching for the first antenna. The method may further include comparing a real-time performance characteristic of the first antenna with a real-time performance characteristic of the second antenna. The method may additionally include, responsive to determining that the second antenna has a stronger real-time performance characteristic than the first antenna while the first antenna is connected to the uplink signal path, switching from the first antenna to the second antenna by connecting the second antenna to the uplink signal path and disconnecting the first antenna from the uplink signal path, and performing impedance matching for the second antenna.