- 专利标题: Flavonoid compounds of low toxicity for biological imaging applications
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申请号: US14740914申请日: 2015-06-16
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公开(公告)号: US09636021B2公开(公告)日: 2017-05-02
- 发明人: Yi Pang , Bin Liu
- 申请人: Yi Pang , Bin Liu
- 申请人地址: US OH Akron
- 专利权人: The University of Akron
- 当前专利权人: The University of Akron
- 当前专利权人地址: US OH Akron
- 代理机构: Renner Kenner Greive Bobak Taylor & Weber
- 主分类号: A61B5/00
- IPC分类号: A61B5/00 ; A61B5/02 ; C07D311/30 ; G01N33/50 ; G01N33/58
摘要:
Flavonoid compounds that are selective for a protein, a portion or a living cell, or a portion of an organism may be used as biological imaging agents. The flavonoid compounds are useful for methods of imaging organisms such as zebrafish embryos and zebra fish. Flavonoid compounds may also be used to detect protein. Advantageously, flavonoids that selectively bind protein, a portion of a living cell, or a portion of an organism may exhibit a florescence “turn-on” mechanism, where the flavonoids that are selectively bound exhibit a florescence response when excited.
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