The invention relates to a filter housing for exchangeable filters, having a housing base for accommodating the filter and having a housing dome which engages over the filter, wherein the housing base and the housing dome are connected to one another by means of an aseptic clamping connection which has a groove-type clamping fitting on the housing base and has a flange-type clamping fitting on the housing dome, these being fixed against one another in their connected position by means of a clamp, wherein the groove-type clamping fitting has a seal groove with a seal by means of which the groove-type clamping fitting can be sealed off with respect to the flange-type clamping fitting, wherein the housing base has a port for the supply of liquid to be filtered and has a port for the discharge of filtered liquid, and wherein the housing base has, transversely with respect to the housing longitudinal axis, a base surface which is adjacent to the face surface of the inserted filter.