- 专利标题： 3′ Equatorial-fluorine-substituted neuraminidase inhibitor compounds, compositions and methods for the use thereof as anti-virals
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申请号： US14372820申请日： 2013-01-17
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公开(公告)号： US09637465B2公开(公告)日： 2017-05-02
- 发明人: Stephen Withers , Hongming Chen , Ricardo Resende , Jennifer Lois Breschkin
- 申请人： THE UNIVERSITY OF BRITISH COLUMBIA
- 申请人地址： CA Vancouver
- 专利权人： The University of British Columbia
- 当前专利权人： The University of British Columbia
- 当前专利权人地址： CA Vancouver
- 代理机构： Bozicevic, Field & Francis LLP
- 代理商 Rudy J. Ng; Carol L. Francis
- 国际申请： PCT/CA2013/050034 WO 20130117
- 国际公布： WO2013/106937 WO 20130725
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; C07D309/00 ; C07D309/14
摘要：
Equatorial 2,3-fluorinated glycosides compounds of formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza, the methods for their preparation, and their pharmaceutical compositions. The therapeutic effect is achieved via inhibition of viral neuraminidases.
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