- 专利标题： Discrimination of blood type variants
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申请号： US14126819申请日： 2012-06-14
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公开(公告)号： US09637788B2公开(公告)日： 2017-05-02
- 发明人: Jorge Ochoa , Monica Lopez , Sergio Escorza , Diego Tejedor , Antonio Martinez , Laureano Simon
- 申请人： Jorge Ochoa , Monica Lopez , Sergio Escorza , Diego Tejedor , Antonio Martinez , Laureano Simon
- 申请人地址： ES Derio
- 专利权人： Progenika Biopharma, S.A.
- 当前专利权人： Progenika Biopharma, S.A.
- 当前专利权人地址： ES Derio
- 代理机构： Klarquist Sparkman, LLP
- 国际申请： PCT/EP2012/061270 WO 20120614
- 国际公布： WO2012/171990 WO 20121220
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34
摘要：
The present invention provides a method for detecting the presence or absence of, or for discriminating between, blood type variants, including RHD*r′s, RHD*DIIIa, RHD*DIVa-2, RHCE*css and RHCE*ce733G. The method comprises genotyping a sample obtained from a human subject at one or more positions in intron 7 of the RHD gene and/or in intron 7 of the RHCE gene. The invention also provides products, in particular, probes, primers and kits for use in the method of the invention.
公开/授权文献
- US20140220567A1 DISCRIMINATION OF BLOOD TYPE VARIANTS 公开/授权日：2014-08-07
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