- 专利标题: Methods and nucleotide fragments of predicting occurrence, metastasis of cancers and patients' postoperative survival in vitro
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申请号: US14378285申请日: 2012-02-13
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公开(公告)号: US09637797B2公开(公告)日: 2017-05-02
- 发明人: Dajun Deng , Jun Zhang , Zhaojun Liu , Jing Zhou , Liankun Gu , Baozhen Zhang
- 申请人: Dajun Deng , Jun Zhang , Zhaojun Liu , Jing Zhou , Liankun Gu , Baozhen Zhang
- 申请人地址: CN Beijing
- 专利权人: Beijing Institute For Cancer Research
- 当前专利权人: Beijing Institute For Cancer Research
- 当前专利权人地址: CN Beijing
- 代理机构: Schwegman Lundberg & Woessner, P.A.
- 国际申请: PCT/CN2012/000169 WO 20120213
- 国际公布: WO2013/120222 WO 20130822
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04 ; G06F19/22
摘要:
Provided in the present invention are a method using in vitro measurement of the content of methylation or demethylation of GFRa1 CpG islands to estimate a risk of tumorigenesis and of tumor metastasis, or postoperative life expectancy, and a nucleotide sequence used.
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