- 专利标题: Selective removal of age-modified cells for treatment of atherosclerosis
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申请号: US13876157申请日: 2011-09-27
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公开(公告)号: US09649376B2公开(公告)日: 2017-05-16
- 发明人: Lewis Gruber
- 申请人: Lewis Gruber
- 申请人地址: US IL Chicago
- 专利权人: Siwa Corporation
- 当前专利权人: Siwa Corporation
- 当前专利权人地址: US IL Chicago
- 代理机构: Evan Law Group LLC
- 国际申请: PCT/US2011/053399 WO 20110927
- 国际公布: WO2012/047629 WO 20120412
- 主分类号: C07K16/44
- IPC分类号: C07K16/44 ; A61K39/395 ; A61K41/00 ; A61B17/32
摘要:
A method of treating atherosclerosis comprises removing AGE-modified cells from a patient. The AGE-modified cells include erythrocytes, intima cells, endothelial cells, smooth muscle cells, macrophages, and foam cells. A variety of techniques, such as ultrasound and binding with an anti-AGE antibody, may be used to identify and remove the AGE-modified cells.
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