- 专利标题： Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
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申请号： US14431789申请日： 2013-09-27
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公开(公告)号： US09650369B2公开(公告)日： 2017-05-16
- 发明人: Guangdi Wang , Quan Jiang , Qiu Zhong , Qiang Zhang , Shilong Zheng
- 申请人： XAVIER UNIVERSITY OF LOUISIANA
- 申请人地址： US LA New Orleans
- 专利权人： XAVIER UNIVERSITY OF LOUISIANA
- 当前专利权人： XAVIER UNIVERSITY OF LOUISIANA
- 当前专利权人地址： US LA New Orleans
- 代理机构： McBee Moore Woodward & Vanik IP, LLC
- 国际申请： PCT/US2013/062302 WO 20130927
- 国际公布： WO2014/052831 WO 20140403
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; C07D277/18 ; C07D277/44 ; A61K31/426 ; A61K31/427 ; C07D277/40 ; C07D277/46 ; A61K45/06 ; A61K31/4439 ; C07D277/52
摘要：
Thiazole analog compounds and their pharmaceutically acceptable salts are disclosed, including pharmaceutical compositions comprising the thiazole analog compounds, either alone or in combination with at least one additional therapeutic agent, and/or with a pharmaceutically acceptable carrier. Methods of using the thiazole analog compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative diseases, such as cancer, are also disclosed.
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