Invention Grant
- Patent Title: Aldose reductase inhibitors and uses thereof
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Application No.: US14541365Application Date: 2014-11-14
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Publication No.: US09650383B2Publication Date: 2017-05-16
- Inventor: Andrew Wasmuth , Donald W. Landry , Shi Xian Deng , Banavara L. Mylari , Ravichandran Ramasamy , Ann Marie Schmidt
- Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: C07D487/04
- IPC: C07D487/04
Abstract:
The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like.
Public/Granted literature
- US20150072989A1 ALDOSE REDUCTASE INHIBITORS AND USES THEREOF Public/Granted day:2015-03-12
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