- 专利标题: Monoclonal antibodies directed against a novel pathogenic west African human immunodeficiency virus type 2 (HIV-2) group F isolate
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申请号: US14263517申请日: 2014-04-28
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公开(公告)号: US09650435B2公开(公告)日: 2017-05-16
- 发明人: Stephen M. Smith , Preston A. Marx, Jr.
- 申请人: Tulane University Health and Sciences Center
- 申请人地址: US LA New Orleans
- 专利权人: The Administrators of the Tulane Educational Fund
- 当前专利权人: The Administrators of the Tulane Educational Fund
- 当前专利权人地址: US LA New Orleans
- 代理机构: McNeill Baur PLLC
- 主分类号: C07K16/10
- IPC分类号: C07K16/10 ; C12N7/00 ; C12Q1/70 ; G01N33/569
摘要:
Isolated monoclonal antibodies that bind to HIV-2 isolate NWK08F are provided. In some embodiments, the antibodies bind a polypeptide comprising the HIV-2NWK08F Env, Pol, or Nef proteins, or fragments thereof, respectively. Antigen-binding fragments and humanized versions of the antibody are also provided.
公开/授权文献
- US20140234332A1 NOVEL HIV-2 ISOLATE 公开/授权日:2014-08-21
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