发明授权
- 专利标题: Antibody based reagents that specifically recognize toxic oligomeric forms of tau
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申请号: US14434742申请日: 2013-10-15
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公开(公告)号: US09650436B2公开(公告)日: 2017-05-16
- 发明人: Michael Sierks , Huilai Tian
- 申请人: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- 申请人地址: US AZ Scottsdale
- 专利权人: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- 当前专利权人: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- 当前专利权人地址: US AZ Scottsdale
- 代理机构: Viksnins Harris & Padys PLLP
- 国际申请: PCT/US2013/065104 WO 20131015
- 国际公布: WO2014/059442 WO 20140417
- 主分类号: C07K16/18
- IPC分类号: C07K16/18 ; G01N33/68 ; C07K16/00 ; C12N15/10 ; A61K39/00
摘要:
The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomelic tau, fibrillar tau or non-disease associated forms of tau.
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