System and methods for securing inter-component communications in an operating system are provided. Systems and methods provided herein secure inter-component communications in an operating system by selectively generating instances when inter-component communication requests occur, whereby each of the generated instances are attached to a newly created blocked permissions list. System and methods further manage the invocation of Application Programming Interfaces by applications or instances in the operating system by determining whether the invocation of the Application Programming Interface is allowed or declined based on the blocked permissions list and default permission list associated with each invoking application or instance.