An injection device (100, 200), including a safety shield (104, 204) and a housing (108, 208). The safety shield (104, 204) has a first end and a surface disposed at a second end thereof for contacting a patient's skin, and a shield tab (164, -240) extending therefrom. The housing (108, 208) is slidably disposed with respect to the safety shield (104, 204) and includes a guide groove (172, 252) for engaging the shield tab (164, 240) to guide movement of the housing (108, 208) relative to the safety shield (104, 204). The guide groove (172, 252) has first (184, 256) and second (188, 260) axial portions and a substantially helical portion (192, 264) connecting the first and second axial portions (184,188, 256, 260). The device (100, 200) also includes a medicament container (120, 220) connected with the housing (108, 208) and having a needle (124, 224) affixed thereto in communication with a medicament disposed within the medicament container (120, 220). The medicament container (120, 220) is displaceable relative to the safety shield (104, 204) from an initial position to an injection position, to a withdrawn position.