A handheld valve dispenser includes a barrel having proximal and distal ends and a fluid chamber adapted to store a fluid. A dispense tip is coupled to the distal end of the barrel and includes a piercing element and a valve seat. The piercing element is configured to pierce the seal and establish an aperture therethrough when the dispense tip is first coupled to the barrel. A valve stem is received within the fluid chamber and is movable between a closed position in which the valve stem sealingly contacts the valve seat to prevent fluid dispense, and an open position for dispensing fluid. The barrel may include an outer barrel member and a disposable inner barrel liner removably received within the outer barrel member.