Invention Grant
- Patent Title: Inhibitors of hepatitis B virus covalently closed circular DNA formation and their method of use
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Application No.: US14382074Application Date: 2013-02-28
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Publication No.: US09657013B2Publication Date: 2017-05-23
- Inventor: Andrea Cuconati , Haitao Guo , Timothy M. Block , Ju-Tao Guo , Xiaodong Xu , Huagang Lu , Dawei Cai
- Applicant: Baruch S. Blumberg Institute , Drexel University
- Applicant Address: US PA Doylestown US PA Philadelphia
- Assignee: Baruch S. Blumberg Institute,Drexel University
- Current Assignee: Baruch S. Blumberg Institute,Drexel University
- Current Assignee Address: US PA Doylestown US PA Philadelphia
- Agency: Saul Ewing LLP
- Agent Kathryn Doyle; Domingos J. Silva
- International Application: PCT/US2013/028150 WO 20130228
- International Announcement: WO2013/130703 WO 20130906
- Main IPC: A61K31/4409
- IPC: A61K31/4409 ; A61K31/505 ; A61K31/4465 ; A61K31/445 ; A61K31/428 ; A61K31/165 ; A61K31/495 ; C07D471/04 ; C07D263/56 ; C07D213/76 ; C07D235/08 ; C07D401/12 ; C07D239/26 ; C07D209/08 ; C07D277/64 ; C07D211/26 ; C07D213/40 ; C07C311/21 ; C07D295/135 ; C07C317/32 ; C07D211/34 ; C07D211/60 ; C07D213/56 ; C07D295/155

Abstract:
Pharmaceutical compositions of the invention comprise covalently closed circular DNA formation inhibitors having a disease-modifying action in the treatment of diseases associated with the formation of covalently closed circular DNA that include hepatitis B infection, and any disease involving formation of covalently closed circular DNA.
Public/Granted literature
- US20150038515A1 INHIBITORS OF HEPATITIS B VIRUS CONVALENTLY CLOSED CIRCULAR DNA FORMATION AND THEIR METHOD OF USE Public/Granted day:2015-02-05
Information query
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