Invention Grant
- Patent Title: Humanized monoclonal antibodies against activated protein C and uses thereof
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Application No.: US14443696Application Date: 2013-11-27
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Publication No.: US09657111B2Publication Date: 2017-05-23
- Inventor: Xiao-Yan Zhao , Zhuozhi Wang , Ji-Yun Kim , Ying Zhu , Jan Tebbe
- Applicant: BAYER HEALTHCARE LLC
- Applicant Address: US NJ Whippany
- Assignee: BAYER HEALTHCARE LLC
- Current Assignee: BAYER HEALTHCARE LLC
- Current Assignee Address: US NJ Whippany
- Agency: Parker Highlander PLLC
- International Application: PCT/US2013/072137 WO 20131127
- International Announcement: WO2014/085527 WO 20140605
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/40 ; G01N33/573
Abstract:
Provided are humanized antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Methods of treatment employing these antibodies are described herein.
Public/Granted literature
- US20150322164A1 HUMANIZED MONOCLONAL ANTIBODIES AGAINST ACTIVATED PROTEIN C AND USES THEREOF Public/Granted day:2015-11-12
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