The present invention discloses a method and device for re-initiating EPS session management procedure. The application of technical solution proposed through embodiment of this invention can enable PGW to determine whether handover operation on MME side is completed through timing by timer and/or instruction message on MME side; if it is completed, re-initiate session management process of corresponding EPS system, thus enabling PGW to timely re-initiate EPS session management procedure, reducing the time for unnecessary waiting, and avoiding resource waste caused by repeated rejection of EPS session management procedure re-initiated when handover procedure is not completed, so as to improve reconnection efficiency of session management process of EPS system and reduce waste of communication resource.