Invention Grant
- Patent Title: Carbazole derivatives acting on 5-HT7 receptor
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Application No.: US14629821Application Date: 2015-02-24
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Publication No.: US09663464B2Publication Date: 2017-05-30
- Inventor: Hyunah Choo , Gyo Chang Keum , Youngjae Kim , Mi Young Yeom
- Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Seoul
- Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Seoul
- Agency: Goldilocks Zone IP Law
- Main IPC: C07D403/06
- IPC: C07D403/06 ; A61K31/496 ; C07D209/86 ; C07D401/06 ; C07D413/06

Abstract:
The present invention provides a carbazole derivative represented by Formula 1: wherein X is CH2 or C(O), Y is selected from NR1R2, piperidinyl groups in which two of the carbon atoms are substituted with R3 and R4, piperazinyl groups in which the nitrogen atom is substituted with R5, and morpholinyl groups, n is an integer from 2 to 5, R1 and R2, which may be identical or different, are each independently selected from C1-C6 alkyl, phenyl, and benzyl, with the proviso that R1 and R2 may be bonded together to form a ring, R3 and R4, which may be identical or different, are each independently selected from hydrogen, C1-C6 alkyl, phenyl, and benzyl, and R5 is selected from C1-C6 alkyl, C1-C4 alkylcarbonyl, phenyl substituted with C1-C4 alkyloxy, hydroxyphenyl, benzyl, and benzoisoxazol-3-yl; or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20160244408A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR Public/Granted day:2016-08-25
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