Invention Grant
- Patent Title: Substituted 6-aza-isoindolin-1-one derivatives
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Application No.: US14706876Application Date: 2015-05-07
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Publication No.: US09663514B2Publication Date: 2017-05-30
- Inventor: Mitsunori Kono , Zhe Nie
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D519/00 ; A61K31/4365 ; A61K31/437 ; A61K31/4985 ; A61K31/519 ; A61K31/5383 ; C07D487/04 ; C07D495/04 ; C07D498/04 ; A61K31/5365

Abstract:
Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, p, R1, R2, R3a, R4, and R5 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, cancer, and other disorders, diseases, and conditions for which inhibition of SYK is indicated.
Public/Granted literature
- US20150274723A1 SUBSTITUTED 6-AZA-ISOINDOLIN-1-ONE DERIVATIVES Public/Granted day:2015-10-01
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