Invention Grant
- Patent Title: Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors
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Application No.: US14749754Application Date: 2015-06-25
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Publication No.: US09669029B2Publication Date: 2017-06-06
- Inventor: Ask Püschl , Jacob Nielsen , Jan Kehler , John Paul Kilburn , Mauro Marigo , Morten Langgård
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: AuerbachSchrot LLC
- Agent Jeffrey I. Auerbach
- Priority: DK2009-01339 20091217
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04 ; C07D471/04 ; A61K45/06 ; A61P25/18 ; A61P25/16 ; A61P25/28 ; A61P25/22

Abstract:
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
Public/Granted literature
- US20150290191A1 Heteroaromatic Phenylimidazole derivatives as PDE10A enzyme inhibitors Public/Granted day:2015-10-15
Information query
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