- 专利标题： Tumor necrosis factor-like ligand 1A specific antibodies and compositions and uses thereof
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申请号： US14539845申请日： 2014-11-12
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公开(公告)号： US09683998B2公开(公告)日： 2017-06-20
- 发明人: Robert Arch , Jun Zhang , Michelle Madar , Tetsuya Ishino , Joel Bard , William Finlay , Orla Cunningham , Ciara Reilly , Peter Brams , Brigitte Devaux , Haichun Huang , Karla Henning
- 申请人： Pfizer Inc. , Bristol-Myers Squibb Company
- 申请人地址： US NY New York US NJ Princeton
- 专利权人： Pfizer Inc.,Bristol-Myers Squibb Company
- 当前专利权人： Pfizer Inc.,Bristol-Myers Squibb Company
- 当前专利权人地址： US NY New York US NJ Princeton
- 代理机构： Ropes & Gray LLP
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; G01N33/68 ; C07K16/28
摘要：
The present invention provides antibodies, or antigen-binding fragment thereof, which specifically bind to tumor necrosis factor-like ligand 1A (TL1A). The invention further provides a method of obtaining such antibodies and nucleic acids encoding the same. The invention further relates to compositions and therapeutic methods for use of these antibodies for the treatment and/or prevention of TL1A mediated diseases, disorders or conditions.
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