- Patent Title: N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
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Application No.: US14034361Application Date: 2013-09-23
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Publication No.: US09693989B2Publication Date: 2017-07-04
- Inventor: Joseph P. Lyssikatos , Julie Marie Hicks , Fredrik P. Marmsater , Qian Zhao
- Applicant: ARRAY BIOPHARMA, INC.
- Applicant Address: US CO Boulder
- Assignee: Array Biopharma, Inc.
- Current Assignee: Array Biopharma, Inc.
- Current Assignee Address: US CO Boulder
- Agency: McDermott Will & Emery LLP
- Main IPC: A61K31/337
- IPC: A61K31/337 ; C07D403/12 ; C07D403/14 ; C07D405/14 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D495/04 ; C07D519/00 ; A61K31/513 ; A61K31/517 ; A61K39/395
Abstract:
This invention provides compounds of Formula I wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.
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