Invention Grant
- Patent Title: Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
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Application No.: US14528142Application Date: 2014-10-30
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Publication No.: US09695240B2Publication Date: 2017-07-04
- Inventor: Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco IT Milan
- Assignee: Genentech, Inc.,Nerviano Medical Sciences S.R.L.
- Current Assignee: Genentech, Inc.,Nerviano Medical Sciences S.R.L.
- Current Assignee Address: US CA South San Francisco IT Milan
- Agent Alex Andrus
- Main IPC: A61K47/48
- IPC: A61K47/48 ; C07K16/28 ; C07K16/30
Abstract:
The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
Public/Granted literature
- US20150051380A1 ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS Public/Granted day:2015-02-19
Information query
