- 专利标题: Lung cancer differential marker
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申请号: US13823922申请日: 2011-09-09
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公开(公告)号: US09696320B2公开(公告)日: 2017-07-04
- 发明人: Hisashi Narimatsu , Akira Togayachi , Yuzuru Ikehara , Hiroyuki Kaji , Atsushi Kuno , Takashi Ohkura , Hideki Matsuzaki , Yoshitoshi Hirao , Jun Iwaki , Minako Abe , Masaharu Nomura , Masayuki Noguchi
- 申请人: Hisashi Narimatsu , Akira Togayachi , Yuzuru Ikehara , Hiroyuki Kaji , Atsushi Kuno , Takashi Ohkura , Hideki Matsuzaki , Yoshitoshi Hirao , Jun Iwaki , Minako Abe , Masaharu Nomura , Masayuki Noguchi
- 申请人地址: JP Tokyo JP Tokyo
- 专利权人: National Institute of Advanced Industrial Science and Technology,Tokyo Medical University
- 当前专利权人: National Institute of Advanced Industrial Science and Technology,Tokyo Medical University
- 当前专利权人地址: JP Tokyo JP Tokyo
- 代理机构: McCarter & English, LLP
- 优先权: JP2010-209932 20100917
- 国际申请: PCT/JP2011/070635 WO 20110909
- 国际公布: WO2012/036094 WO 20120322
- 主分类号: G01N33/574
- IPC分类号: G01N33/574 ; G01N33/68 ; C07K14/47 ; C07K16/28 ; C07K16/30
摘要:
An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on increase or decrease in protein expression level between cancer patients and healthy persons. Another object of the present invention is to develop and provide a glycan marker capable of distinguishing histological types of lung cancer. Of serum glycoproteins, glycopeptide and glycoprotein groups whose glycan structures were altered specifically in lung cancer cell culture supernatants were identified, and they are provided as lung cancer differential markers.
公开/授权文献
- US20130288272A1 LUNG CANCER DIFFERENTIAL MARKER 公开/授权日:2013-10-31