An audio output control method and apparatus using a wired/wireless communication system is provided. An audio output control method of an audio output device connected to at least one other audio output device according to the present disclosure includes converting specific audio data to at least one modified audio signal designated to the respective audio output devices, playing at least one of the modified audio signals through a channel designated to the specific audio data, and transmitting a remaining of the modified audio signals to the at least one other audio output device, wherein the modified audio signals include at least one of sound sources and channel characteristics of the specific audio data.