Method and systems for autofocus triggering focusing are disclosed herein. In one example, a system may include a lens, a memory component configured to store lens parameters of the lens and regions of focus corresponding to the lens parameters, and a processor coupled to the memory and the lens. The processor may be configured to focus the lens on a target object at a first instance of time, receive information indicative of distances from an imaging device to the target object over a period of time, obtain lens parameters of the lens, and determine a region of focus, and trigger the lens to re-focus on the target object if the distance to the target object indicates the target object is outside of the region of focus and the distance to the target object is unchanged for a designated time period.