- Patent Title: Substituted spiropiperidinyl compounds useful as GPR120 agonists
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Application No.: US14434524Application Date: 2013-10-11
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Publication No.: US09708270B2Publication Date: 2017-07-18
- Inventor: Mariappan Chelliah , Hong Dong Chu , Jason M. Cox , John S. Debenham , Keith Eagen , Ping Lan , Clare London , Michael A. Plotkin , Unmesh Shah , Christopher Joseph Sinz , Zhongxiang Sun , Henry M. Vaccaro , Srikanth Venkatraman
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Baerbel R. Brown; Catherine D. Fitch
- International Application: PCT/US2013/064472 WO 20131011
- International Announcement: WO2014/059232 WO 20140417
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D491/107 ; C07D221/20 ; C07D201/04 ; C07D401/04 ; C07D405/10
Abstract:
The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.
Public/Granted literature
- US20150274672A1 SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS Public/Granted day:2015-10-01
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