- 专利标题： Methods for treating pain and screening analgesic compounds
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申请号： US12307953申请日： 2007-07-17
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公开(公告)号： US09717775B2公开(公告)日： 2017-08-01
- 发明人: J. Michael McIntosh , Baldomero M. Olivera , Michael A. Ellison , Michelle Vincler
- 申请人： J. Michael McIntosh , Baldomero M. Olivera , Michael A. Ellison , Michelle Vincler
- 申请人地址： US UT Salt Lake City
- 专利权人： University of Utah Research Foundation
- 当前专利权人： University of Utah Research Foundation
- 当前专利权人地址： US UT Salt Lake City
- 代理机构： Christensen O'Connore Johnson Kindness PLLC
- 国际申请： PCT/US2007/016163 WO 20070717
- 国际公布： WO2008/011006 WO 20080124
- 主分类号： A61K38/03
- IPC分类号： A61K38/03 ; A61K38/10 ; C12Q1/00 ; G01N33/53 ; A61K38/17 ; G01N33/94
摘要：
The present invention relates to the use of compounds that block the α9α10 subtype of the nicotinic acetylcholine receptor (nAChR) for treating pain, such as neuropathic pain and inflammatory pain, and inflammatory disorders, such as arthritis. The present invention also relates to screening compounds to identify analgesic agents that block the α9α10 subtype of the nAChR.