Invention Grant
- Patent Title: Substituted thiazole or oxazole P2X7 receptor antagonists
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Application No.: US15115963Application Date: 2015-02-04
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Publication No.: US09718812B2Publication Date: 2017-08-01
- Inventor: Paolo Pevarello , Stefan Lohmer , Chiara Llberati , Pierfausto Seneci , Cristina Pesenti , Adolfo Prandi
- Applicant: Axxam S.P.A.
- Applicant Address: IT Bresso (MI)
- Assignee: Axxam S.P.A.
- Current Assignee: Axxam S.P.A.
- Current Assignee Address: IT Bresso (MI)
- Agency: Silvia Salvadori, P.C.
- Agent Silvia Salvadori
- Priority: EP14154038 20140205
- International Application: PCT/EP2015/052316 WO 20150204
- International Announcement: WO2015/118019 WO 20150813
- Main IPC: C07D417/06
- IPC: C07D417/06 ; C07D413/14 ; C07D277/30 ; C07D417/14 ; C07F7/18 ; C07D277/28 ; C07D263/32 ; C07D413/06
Abstract:
The present invention refers to novel substituted thiazole and oxazole compounds of formula (I) having P2X7 receptor (P2X7) antagonistic properties. The compounds are useful in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans.
Public/Granted literature
- US20170008883A1 SUBSTITUTED THIAZOLE OR OXAZOLE P2X7 RECEPTOR ANTAGONISTS Public/Granted day:2017-01-12
Information query
