Invention Grant
- Patent Title: Composition for preventing or treating renal fibrosis comprising dimethylfumarate as active ingredient
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Application No.: US14767767Application Date: 2013-02-20
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Publication No.: US09724320B2Publication Date: 2017-08-08
- Inventor: In Kyu Lee , Keun Gyu Park , Chang Joo Oh , Han Jong Kim , Joon-Young Kim
- Applicant: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION , KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL
- Applicant Address: KR Daegu
- Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
- Current Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
- Current Assignee Address: KR Daegu
- Agency: Marshall, Gerstein & Borun LLP
- Priority: KR10-2013-0015431 20130213
- International Application: PCT/KR2013/001303 WO 20130220
- International Announcement: WO2014/126285 WO 20140821
- Main IPC: A61K31/225
- IPC: A61K31/225 ; A61K9/00 ; A61K9/14 ; A61K9/20 ; A23L33/10
Abstract:
The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-β/Smad signaling, and thus is useful for preventing or treating renal fibrosis.
Public/Granted literature
- US20160067206A1 COMPOSITION FOR PREVENTING OR TREATING RENAL FIBROSIS COMPRISING DIMETHYLFUMARATE AS ACTIVE INGREDIENT Public/Granted day:2016-03-10
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