Invention Grant
- Patent Title: Methods of treating cancer using PD-1 axis binding antagonists and MEK inhibitors
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Application No.: US14236064Application Date: 2012-08-01
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Publication No.: US09724413B2Publication Date: 2017-08-08
- Inventor: Heather Maecker , Bryan Irving
- Applicant: Heather Maecker , Bryan Irving
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2012/049233 WO 20120801
- International Announcement: WO2013/019906 WO 20130207
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/30 ; A61K31/4184 ; A61K31/4355 ; A61K31/44 ; A61K31/4523 ; A61K31/519 ; A61K47/48 ; A61K39/00
Abstract:
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and a MEK inhibitor and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.
Public/Granted literature
- US20140341902A1 METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND MEK INHIBITORS Public/Granted day:2014-11-20
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