A dialysis service box for centralized control and plumbing arrangement of a dialysis machine is disclosed. The dialysis service box includes a plumbing arrangement with a warm water inlet and a cold water inlet in fluid flow communication with a temperature mixing component. The thermostatic mixing component mixes the cold water and the warm water to produce mixed water maintained at a predetermined temperature between the temperature of the cold water and the temperature of the warm water. The dialysis service box can be universally installed to operate, control and adjust any dialysis machine that requires supply connection, waste connection, backflow preventer, thermostatic mixing component, a trap primer, or any combination of the foregoing.