A front wheel supporting frame structure of a saddle-ride vehicle includes a main frame, upper and lower arms and a lower frame. The main frame has a front portion and a rear portion. The main frame includes an upper connection portion, a lower connection portion, and an extending portion. The extending portion extends downward. The upper arm has an upper front end portion and an upper rear end portion. The upper rear end portion is movably connected to the upper connection portion. The lower arm has a lower front end portion and a lower rear end portion. The lower rear end portion of is movably connected to the lower connection portion. The lower frame includes a bottom portion and an upright portion. The bottom portion extends in the vehicle front-rear direction. The upright portion has a top portion connected to the extending portion.