Invention Grant
- Patent Title: HDAC inhibitors
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Application No.: US15004039Application Date: 2016-01-22
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Publication No.: US09725407B2Publication Date: 2017-08-08
- Inventor: Alan Hornsby Davidson , David Festus Charles Moffat , Francesca Ann Day , Alastair David Graham Donald
- Applicant: GlaxoSmithKline Intellectual Property Development Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: GlaxoSmithKline Intellectual Property Development Limited
- Current Assignee: GlaxoSmithKline Intellectual Property Development Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Duke M. Fitch; Kathryn A. Lutomski; Edward R. Gimmi
- Priority: GB0619753.7 20061006
- Main IPC: C07C259/06
- IPC: C07C259/06 ; C07D211/58 ; C07D211/34 ; C07C311/19 ; C07D213/56 ; C07D215/22 ; C07D241/04 ; C07D333/70 ; C07D409/12 ; C07D471/04
Abstract:
Compounds of formula (I) inhibit HDAC activity: wherein A, B and D independently represent ═C— or ═N—; W is a divalent radical —CH═CH— or CH2CH2—; R1 is an ester group; R2 is the side chain of a natural or non-natural alpha-amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.
Public/Granted literature
- US20160137594A1 HDAC INHIBITORS Public/Granted day:2016-05-19
Information query
