Invention Grant
- Patent Title: Substituted 4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines as factor XIa inhibitors
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Application No.: US15183051Application Date: 2016-06-15
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Publication No.: US09725435B2Publication Date: 2017-08-08
- Inventor: Michael J. Orwat , Donald J. P. Pinto , Leon M. Smith, II , James R. Corte , Shefali Srivastava
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/04 ; C07D401/10 ; C07D401/14 ; C07D413/14 ; C07D217/26 ; C07D487/04 ; C07D401/12
![Substituted 4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines as factor XIa inhibitors](/abs-image/US/2017/08/08/US09725435B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.
Public/Granted literature
- US20160289209A1 SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS Public/Granted day:2016-10-06
Information query
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