Invention Grant
- Patent Title: Modulators of CFTR
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Application No.: US14633278Application Date: 2015-02-27
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Publication No.: US09725440B2Publication Date: 2017-08-08
- Inventor: Sara Hadida-Ruah , Mark Miller , Brian Bear , Jinglan Zhou , Jason McCartney , Peter Grootenhuis
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D213/75 ; C07D401/04 ; A61K31/444 ; G01N33/50
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating CFTR mediated diseases using compounds of the present invention.
Public/Granted literature
- US20150166516A1 MODULATORS OF CFTR Public/Granted day:2015-06-18
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