- Patent Title: Cycloalkyl nitrile pyrazolo pyridones as Janus kinase inhibitors
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Application No.: US14778019Application Date: 2014-03-19
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Publication No.: US09725445B2Publication Date: 2017-08-08
- Inventor: Matthew Lloyd Childers , Christopher Dinsmore , Peter Fuller , David Guerin , Jason David Katz , Qinglin Pu , Mark E. Scott , Christopher F. Thompson , Hongjun Zhang , Danielle Falcone , Luis Torres , Jason Brubaker , Hongbo Zeng , Jiaqiang Cai , Xiaoxing Du , Chonggang Wang , Yunfeng Bai , Norman Kong , Yumei Liu , Zhixiang Zheng
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; Catherine D. Fitch
- Priority: WOPCT/CN2013/072867 20130319
- International Application: PCT/CN2014/000296 WO 20140319
- International Announcement: WO2014/146490 WO 20140925
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D519/00
Abstract:
Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
Public/Granted literature
- US20160280704A1 CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS Public/Granted day:2016-09-29
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