Invention Grant
- Patent Title: Crystalline forms of a bruton's tyrosine kinase inhibitor
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Application No.: US15497896Application Date: 2017-04-26
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Publication No.: US09725455B1Publication Date: 2017-08-08
- Inventor: Norbert Purro , Mark Stephen Smyth , Erick Goldman , David D. Wirth
- Applicant: Pharmacyclics LLC
- Applicant Address: US CA Sunnyvale
- Assignee: Pharmacyclics LLC
- Current Assignee: Pharmacyclics LLC
- Current Assignee Address: US CA Sunnyvale
- Agency: Foley Hoag LLP
- Main IPC: C07D487/00
- IPC: C07D487/00 ; C07D295/00 ; C07D487/04

Abstract:
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Public/Granted literature
- US20170226112A1 CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR Public/Granted day:2017-08-10
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