Invention Grant
- Patent Title: Phosphoinositide 3-kinase inhibitors with a zinc binding moiety
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Application No.: US14539327Application Date: 2014-11-12
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Publication No.: US09725461B2Publication Date: 2017-08-08
- Inventor: Xiong Cai , Haixaio Zhai , Chengjung Lai , Changgeng Qian
- Applicant: Curis, Inc.
- Applicant Address: US MA Lexington
- Assignee: Curis, Inc.
- Current Assignee: Curis, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar Harlan; Carolyn Elmore
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D491/04 ; C07D413/14 ; A61K31/535
Abstract:
The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
Public/Granted literature
- US20150203509A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY Public/Granted day:2015-07-23
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