Invention Grant
- Patent Title: Methods of treatment using anti-GDF15 antibodies
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Application No.: US14863870Application Date: 2015-09-24
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Publication No.: US09725505B2Publication Date: 2017-08-08
- Inventor: Lorena Lerner , Sandra Abbott , Ailin Bai , Ting Chen , Maria I. Chiu , Qing Liu , Laura Poling , Nianjun Tao , Solly Weiler , Zhigang Weng , William M. Winston, Jr. , Jeno Gyuris
- Applicant: AVEO Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/22 ; A61K45/06 ; A61K39/00
Abstract:
Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
Public/Granted literature
- US20160083465A1 ANTI-GDF15 ANTIBODIES Public/Granted day:2016-03-24
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